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和肝助脾饮对免疫性肝损伤小鼠脾脏T和B淋巴细胞功能的影响

EFFECT OF HEGANZHUPIYIN ON SPLEEN T AND B LYMPHoCYTES PROLIFERATIONO OF LIVER IMMUNE DAMAGE MICE

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【作者】 马正业周勇严宣佐张丽

【Author】 Ma Zhengye;Zhou Yong;Yan Xuanzuo;et al 1996;10(1):29(Department of Infectious Disease)

【机构】 北京中医药大学

【摘要】 C57BL/6小鼠脾脏T和B淋巴细胞的增殖能力,在受到免疫性肝损伤后下降(T细胞16574±776→2880±134cpm,P<0.01;B细胞16064±325→14904±241cpm,P<0.05),和肝助脾饮不仅能使免疫性肝损伤小鼠脾脏T和B淋巴细胞增殖能力下降得到改善(T细胞6188±129cpmP<0.01;B细胞有增高趋势15600±268cpm),而且正常小鼠应用后亦明显提高(T细胞31454±472cpm,P<0.01;B细胞29598±642cpm,P<0.01)。提示和肝助脾饮能改善免疫功能,减轻小鼠的免疫损伤。

【Abstract】 Splenic T and B lymphocytes proliferation of C<,BL/6 mice with liver immune damage decreas as compare with noimal mice(T cell proliferation 16 574±776→2880±134 cpm,P<0.01 and B cell proliferation 16 064 ± 325→14 904±241 cpm,P<0.05).The Heganzhupi Yin(a fluid form of a formulation consisting several traditional Chinese herbs)not only can reduce the decrease of T lymphocytes proliferation of liver immune damage C57 BL/6 mice(T cell 6 188±129 clJm,P<0.01 and show a B cell enhancement tendency 15600±268 cpm).but also increase splenic T and B lymphocytes proliferation of normal mice(T cell 31 454±472 cpm,P<0.01 and B cell 29 598 ±642 cpm,P<0.01.respectnehy).It is demonstrated that Heganzhupi Yin can improve immune function and reduce liver dam-age.

【关键词】 小鼠免疫性疾病肝疾病和肝助脾饮
【Key words】 miceimmune diseasehepatic diseaseHeganzhupi Yin
  • 【文献出处】 中日友好医院学报 ,JOURNAL OF CHINA-JAPAN FRIENDSHIP HOSPITAL , 编辑部邮箱 ,1996年01期
  • 【分类号】R575
  • 【下载频次】31
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