【摘要】 应用酶联亲和组化法对５４例食管鳞状上皮癌及１２例正常食管粘膜进行雌激素受体和孕激素受体检测。结果表明，食管鳞状上皮癌的雌激素受体阳性率为４２．６％，孕激素受体阳性率为３７．０％。正常食管粘膜均为阴性。提示食管鳞状上皮癌中确有雌激素受体及孕激受体存在，同时其阳性率与组织学分级、性别有明显关系，而与病理形态、年龄、淋巴结转移无关。该研究为选择性应用内分泌治疗食管鳞状上皮癌提供了理论依据。更多还原

【Abstract】 cases of esophageal squamous cell carcinoma and 12 normal controls wereassayed with E2-HRP and Pg-HRP immunohistochemical method for estroge receptor(ER)andprogesterone receptor(PR).No ER and PR were found in normal groups,while ER and PRpositive rates were 42.6%and 37.0%respectively in esophageal squamous cell carcinoma. Thepositive rate was correlated with the sex and diffcrentiation of carcinoma,but not withpathological types,age and lymphatic spread.Assay of ER and PR may guide the clinicalendocrinol therapy in esophagcal squamous cell carcinoma.更多还原