【摘要】 本文探讨桥本氏病并发甲状腺癌的机理及发病关系。作者从１９７６年至１９９４年，手术治疗桥本氏病９５例（均经病理检查证实），发现同时并存甲状腺癌６例（６．３％）。患者均为女性，平均年龄３０．３岁；其中乳头状癌５例、滤泡状癌１例，２例并发甲状腺机能亢进。术前５例并发癌被漏诊或误诊，主要原因是癌灶较小，被肿大的甲状腺掩盖或医生对其缺乏认识。对３例作了根治手术，另３例仅作双侧甲状腺次全切除。术后随访１～１７年，无癌复发或转移者。作者强调术中切片检查，根据病理类型进行手术。更多还原

【Abstract】 Hashimoto’sdiseaseassociatedwiththyroidcancerisnotcommon.FromJanuary1976toDecember1994,atotalof95patientswithHashimoto’sdiseaseweretreatedsurgicaly.Six(5papil-lary1folicular)of95patientshadthyroidcancerwhichwasconcomitantlyrevealedpathologicaly.Theywerealwomenwithmeanageof30.3years.Thesizeoftumorwas0.3～2.0cm.Folow-upfor1～17yearsshowedthattheywerealaliveandhealthy.Twopatientsweremisdiagnosedashavinganaplasticcarcinomabutthedefinitivediagnosisbyimmunohistochemicalanalysiswasthyroidmalignantlym-phoma(B-celtype).Hashimoto’sdiseaseandthyroidcancerrelationship,diagnosis,andtreatmentarediscussed.更多还原