【摘要】 为探讨甲状腺癌侵犯前上纵隔的机理,作者分析了1962～1994年治疗侵犯前上纵隔的晚期甲状腺癌24例,其中乳头状腺癌16例,滤泡样腺癌、髓样癌各3例,低分化癌2例。治疗方法均为甲状腺癌颈胸联合根治术,肿瘤完整切除16例,肉眼残留8例。术后补充放疗9例。5年生存率64.7%,10年生存率46.7%,生存5年以上者均为乳头状腺癌患者。提示影响预后的主要因素是病理类型。更多还原

【Abstract】 Thyroid carcinoma may invade the upper mediastinum by direct extension of the primary or metas-tases to the paratracheal or retroclavicular-parajugular lymph nodes. From 1962 to 1994,24 (16 papil-lary, 3 follicullar, 3 medullary, and 2 undifferetiated) of 1204 thyroid cancer patients (2%) received trans-sternal cervico-mediastinal tumor resection. The tumor was resected totally in 16 patients, and residual at the time of initial operation in 8 patients. 9 patients were recived radiation therapy afer surg- ery. The five-year survival was 64.7% and the 10-year survival was 46.7%. All of the patients who lived over 5 years had papillary carcinoma.更多还原