【摘要】 用放射免疫法测定了８０例慢性肾脏病患者血浆皮质醇的变化。结果显示：无氮质血症的慢性肾小球疾病患者血浆皮质醇低于正常对照组（Ｐ＜０．００１），其浓度随肾功能的降低而增加。慢性肾脏病常并发感染、高血压等应激因素，使血浆皮质醇持续升高，从而可能是参与肾小球疾病进展至终末期肾衰的因素之一。更多还原

【Abstract】 Thechangeofplasmacortisolwasmeasuredwithradioimmunoassayfor80patientswithchronicrenaldisease.Theresultsshowedthat:Thecortisollevelofabovepatientswithoutazotemiawaslowerthannor-malcontrol(P<0.001)andwasrisenwiththedeclineofrenalfunction.Chronicrenaldiseasesoftencomplicatewithstressfactors,suchasinfection、hypertensionandsoon,whichleadtotheincreaseofplasmacortisolandaceleratethedevelopmentfromglomerulardiseasetoend-stagerenalfailure.更多还原