【摘要】 为了明确沥青烟气的致皮肤癌作用,我们对沥青烟气进行了动物实验研究。方法:将100只昆明种小鼠随机分为 A、B 两组。A 组小鼠每天在一染毒箱中暴露于煤焦沥青烟气3小时,每周6天,箱内烟气平均浓度为0.17mg/L,4个月后停止,另再观察4个月。B 组为空白对照组。结果:8个月中,A 组有40只小鼠发生皮肤肿瘤(83.3%),其中32只小鼠有皮肤鳞状细胞癌(66.7%),并有8例发生淋巴结转移。B 组无皮肤肿瘤发生。本研究证实:煤焦沥青烟气与液态沥青一样,具有强烈的致皮肤癌作用。更多还原

【Abstract】 In this study,100 mice were divided into two groups(group A and B)to study the car- cinogenic effect of pitch smoke on skin.Mice in group A were exposed to coal tar pitch smoke(CTPS) 3 hours a day in a box 6 days per week.The average concentration of CTPS in the box was 0.17mg/L. The duration of exposure was 4 months.These mice were followed up for another 4 months.Group B was designed as a control.After eight months,skin neoplasms were found in 40 mice(83.33%)in group A,of which squamous cell carcinomas were found in 32 mice(66.67%).Lymph node metastasis of the carcinoma was found in 8 mice.No skin tumor was found in group B.The result of present study shows that CTPS has strong carcinogenic effect on skin.更多还原