【摘要】 设计合成了５个尿嘧啶－１－乙醛缩（Ｎ４－取代氨基硫脲）衍生物并对其进行了抗家蚕核型多角体病毒及家蚕细胞质型多角体病毒活性实验。结果表明，这５个化合物具有不同程度的抑制作用。更多还原

【Abstract】 Five uracil-1-acetaldehyde (N￣4 -substituted thiosemicarbazones were synthesized by condensation of N￣4-substituted thiosemicarbazides with uracil-1-acetaldehyde.Antiviral activity against Nuclear Polyhedrosis Virus(NPV) and Cytoplasic Polyhedrosis Virus (CPV) in silkworms were tested in vivo.The results showed that all compounds possessed significant activity against NPV and two of them exhibited high activity against CPV.更多还原