【摘要】 观察阿芬太尼用于静脉复合麻醉对于气管插管时及术中、术后循环的影响。选择ASA Ⅰ～Ⅱ级择期手术患者40例:实验组（A组）20例,用阿芬太尼40μg·kg^-1诱导,维持量每分钟1μg·kg^-1;对照组（B组）20例,用芬太尼4μg·kg^-1诱导,维持量每分钟0.1μg·kg^-1,维持期均吸入1%～1.5%安氟醚,酌情追加维库溴铵。分别记录两组入室时、给诱导量后1～5分钟、插管后0～2分钟及拔管后0～10分钟的血压（收缩压、舒张压、平均压）、心率变化。实验结果表明阿芬太尼40μg·kg^-1能抑制插管时的心血管反应,1μg·kg^-1·min^-1用于静吸复合全麻时,维持手术中循环稳定,术后呼吸恢复快,因此适于作静点维持麻醉。更多还原

【Abstract】 The influences of alfentanil on the iutubation response and the homodynamic changes during and after operation were studied. 40 patients （ASA Ⅰ～Ⅱ） were randomly divided into study group （n=20） and control group （n=20）. The patients recieved alfentanil 40μg·kg^-1（study group） or fentanyl 4μg·kg^-1（control group） for induction and alfentanil 1μg·kg^-1·min^-1 or fentanyl 0.1μg·kg^-1·min^-1. with 1%～1.5% enflurane for mamtenance of anesthesia. respectively. SP, DP, MAP, HR were recorded before and 1～5 min after induction, 0～2 mins after intubation. The results showed that the intubation responses can be depressed by atfentanil 40μg·kg^-1 and hemodynamics were stable during and after anesthesia with alfentanil 1μg·kg^-1·min^-1 and 1%～1.5% enflurane. It is suggested that the alfentanil can be used for induction as well as for maintenance of anesthesia.更多还原