节点文献
131I-MIBG在异位和(或)恶性嗜铬细胞瘤定位诊断中的应用
The value of diagnosis of aberrant and(or) malignant pheochromocytoma with 131I-MIBG imaging
【摘要】 CT或其他影像学方法定位诊断异位和(或)恶性嗜铬细胞瘤及其转移灶常有困难,本研究对25例经手术或病理检查诊断为异位和(或)恶性嗜铬细胞瘤及其转移灶的患者行131I-间位碘代苄胍(MIBG)定位显像,部分病例与CT和B超进行了比较。结果25例131I-MIBG显像的检出率为100%;CT和B超的检出率各为45.5%和81.8%。CT检出率低主要由于小而分散的肿瘤在腹腔内不易与肠腔的断面相区分所致。131I-MIBG诊断异位和(或)恶性嗜铬细胞瘤及其转移灶,特别对腹腔内小而分散的肿瘤具有较高的灵敏度及特异性。
【Abstract】 PURPOSE The diagnostic value of 131I-MIBG scintigraphy for aberrant and (or) malignant pheochromocytoma was retrospectly studied. METHODS 131I-MIBG imaging was performed in 25 cases with aberrant and (or) malignant pheochromocytoma, and in some cases compared with the findings of CT and B ultrasound. RESULTS The detective rate of 25 cases was 100 % in 131I-MIBG imaging, 45.5% in CT and 81.8% in B ultrasound. The low detective rate in CT scan may be due to undifferentiation between the diffuse small abdominal lesions and the cross sectional intestine. CONCLUSIONS 131I-MIBG imaging scintigraphy has very high sensitivity and specificity for diagnosing aberrant and (or) malignant pheochromocytoma especially for the diffuse and small abdominal lesions.
【Key words】 Pheochromocytoma Meta-iodobenzylguanidine Iodime radioisotopes Radionuclide imaging;
- 【文献出处】 中华核医学杂志 ,Chinese Journal of Nuclear Medicine , 编辑部邮箱 ,1996年02期
- 【分类号】R736.6
- 【被引频次】11
- 【下载频次】50