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99mTc-MIBI显像诊断自主功能性甲状腺结节

Diagnosis of Plummer’s disease by99mTc-MIBI thyroid imaging

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【作者】 李方周前

【Author】 Li Fang Zhou Qian.PUMC Hospital,CAMS,Beijing 100730

【机构】 北京协和医院核医学科北京协和医院核医学科

【摘要】 报告20例自主功能性甲状腺结节显像的诊断意义。9例(99m)TcO4-显像示正常甲状腺组织完全被抑制的病例,8例(99m)Tc-甲氧基异丁基异腈(MIBI)显像正常甲状腺组织显影清晰;11例正常甲状腺组织不全抑制的病例,(99m)Tc-MIBI 显像8例显影较(99m)TcO4-显像清晰,3例未见变化。虽然(99m)Tc-MIBI 显像与 TSH 刺激试验显像的原理不同,但它能使功能受抑制的正常甲状腺组织显影,能够帮助鉴别诊断甲状腺结节的自主功能性,与 TSH 刺激试验比较,具有简便、无过敏反应的优点。

【Abstract】 PURPOSE The visualization of suppressed thyroid tissue in Plummer’s disease was studied by 99mTc-MIBI thyroid imaging.METHODS 20 patients of Plummer’s disease with totally or partially suppressed normal thyroid tissue were studied first by 99mTcO4- and then by 99mTc-MIBI thyroid imaging.RESULTS The suppressed tissue was clearly visualized in 8 out of 9 cases with totally suppressed normal thyroid tissue,while in 11 cases with partially suppressed normal thyroid tissue.The suppressed tissue became clearer in 8 and no change in 3 as compared with their 99mTcO4- imaging.CONCLUSIONS The results suggested that 99mTc-MIBI thyroid imaging may he used as a substitute for post-TSH stimulation imaging in the diagnosis of Plummer’s dis- ease.This method is relatively simple and has no TSH-related allergic reaction.

【关键词】 Plummer 病放射性核素显像腈类
【Key words】 Plummet diseaseRadionuclide imagingNitrilesTechnetium
  • 【文献出处】 中华核医学杂志 ,Chinese Journal of Nuclear Medicine , 编辑部邮箱 ,1996年01期
  • 【分类号】R817.4
  • 【被引频次】1
  • 【下载频次】28
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