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高山红景天多糖降血糖作用——不同给药途径的比较

Studies on Hypoglycemic Effect of Rhodiola sachalinensis A.Bor. Polysaccharides:Comparison of Administration in Different Ways

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【作者】 程秀娟; 邸琳; 吴岩; 刘新宇; 任乔林;

【Author】 Cheng Xiujuan, Di Lin,Wu Yan, Liu Xinyu and Ren Qiaolin (Jilin Provincial Academy of TCM and Materia Medica,Changchun 130021)

【机构】 吉林省中医中药研究院;

【摘要】 分别给小鼠腹腔注射RSPA和B各100,50mg/kg,结果表明RSPB为高山红景天降血糖作用的有效部分,经多种途径给药证明RSPB不能经胃肠吸收而发挥降血糖作用,但经sc,im,ip,iv均可产生明显的降血糖作用

【Abstract】 When Rhodiola sachalinensis polysaccharides A and B (RSP A and RSP B)were intraperitoneally injected to mice at dosages of 50mg/kg and 100mg/kg,the result showed that RSP B was the effective hypoglycemic ingredient of Rhodiola sachalinensis .When mice were administrated in different ways,it was shown that RSP B did not possess significant hypoglycemic effect through absorption in the instestines.However,RSP B does possess significant hypoglycemic effect if administrated subcutaneously,intramuscularly,intraperitoneally and intravenously.

  • 【文献出处】 中国中药杂志 ,CHINA JOURNAL OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1996年11期
  • 【分类号】R285.6
  • 【被引频次】90
  • 【下载频次】428
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