【摘要】 根据４种贝母抑制由ＰＡＦ诱导血小板聚集部位筛选结果，从平贝母的水溶性活性部位中分得胸苷和腺苷等成分。试验表明腺苷为抑制聚集的主要成分。提示核苷类可能是贝母中除生物碱外的另一类活性成分。更多还原

【Abstract】 Based on platelet aggregation induced by platelet activating factor(PAF) .the active fraction with in-hibiting effect was sereened from four spacies of Chinese drung Beimu.the bulbs of Fritillaria przewalskii, F. us-suriensis. F. anhuiensis and F. thunbergii.According to the experimental results. the active water soluble fraction ofF. ussuriensis was further studied. Two nucleosides, thymidine and adenosine were isolated. Platelet aggregation as-say shows that adenosine is the chief aggregation inhibitor with 1%= 42 at 5μm. It is suggestad that nucleosides maybe the other type of active constituent besides alkaloids in the Fritiaria plants.更多还原