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NIDDM患者左心室功能与高胰岛素血症的关系探讨

Relationship of the left ventricular function to hyperinsulinemia in patients with NIDDM

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【作者】 杨立勇王中心严孙杰赵淑好刘东晖陈济添阮琴韵

【Author】 Yang Liyong;Wang Zhongxin;Yan Sunjie,et al(Department of Endocrinology,The First Affiliated Hospital of Fujian Medical College,Fuzhou 350005)

【机构】 福建医学院附属第一医院内分泌科

【摘要】 观察98例NIDDM患者彩色多普勒超声心动图、血清胰岛素和C肽释放试验的检测结果,显示在左心室功能障碍的患者血清胰岛素水平、胰岛素/C肽比值均较左心室功能正常的患者增高,而胰岛素敏感性指数则降低,提示高胰岛素血症可能参与NIDDM患者左心室功能异常的发生机制。

【Abstract】 Color Doppler echocardiography,glucose,insulin and C-peptide of fasting and stimulating state(after test-meal) were determined in 98 NIDDM patients.The results showed that the level of serum insulin and insulin/C-peptide ratio were increased,but glucose/insulin ratio was decreased in the diabetics with left ventricularLV)dysfunction as compared with those of normal LV function.These data suggested that hyperinsulinemia might participate in the pathogenesis of abnormal LV function in the patients with NIDDM.

  • 【文献出处】 中国糖尿病杂志 ,CHINESE JOURNAL OF DIABETES , 编辑部邮箱 ,1996年02期
  • 【分类号】R587.102
  • 【下载频次】15
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