【摘要】 本文对２００例高血压患者进行了２４小时动态血压监测（ＡＰＢＭ），并且全部病例进行了彩色多普勒超声检查。根据心肌重量（ＬＶＭ）和心肌重量指数（ＬＶＭＩ），将左室壁分为有无肥厚两组。结果发现：夜间平均收缩压和平均舒张压下降率与ＬＶＭ和ＬＶＭＩ呈显著负相关。更进一步研究说明，血压昼夜节律消失的高血压患者，左室肥厚检出率为４３％。左室肥厚者血液动力学改变Ｅ峰减低，Ａ峰明显增高，Ｅ峰减速度（ＥＤＣ）减小，检出率８１．９％高于非左室肥厚者，Ｐ＜０．００１。收缩功能与ＬＶＭ、ＬＶＭＩ呈显著负相关。表明高血压患者夜间血压水平与血压昼夜节律状况对左室肥厚发生和发展起主导作用，而左室肥厚的有无又与彩色多普勒超声的血液动力学改变具有密切关系。更多还原

【Abstract】 twenty-four hours ambulatory blood pressure monitoring(ABPM)and colour Doppler echocardiography were performed for 200 hypertensive patients According to left ventricular mass(LVWI)and left ventricular mass index(LVMI),We divided the patients into hypertrophy group and non-hypertrophy group.The results discovered that declined rate of the night mean systolic pressure and mean diastolic pressure correlated negatively with LVM and LVMI.Further study indicated that hypertensive patients without blood pressure day-and-hight rhythm-crack-out rate of left ventricular hypertrophy was 43%,Alterations of hemodynamic in left ventricular hypertrophy were:E peak decreased,obvious A peak increased,EDC decreased,checkout rate was 81.9%highly than left ventricalar non-hypertrophy,P<0.001.Systolic function correlated negatively with LVM and,LVMI.The results indicated that night blood pressure level and blood pressure day-andnight rhythm state took leading role on the occurrence and development of left ventricular hypertrophy in hypertensive patients. Left ventricular hypertophy and left ventricular non-hypertrophy correlated with hemodynamic alteration of colour Doppler echocardiography.更多还原