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急性脑血管病患者血清肿瘤坏死因子α的变化

Changes of serum concentrations of tumor necrosis factor-α in patients with acute cerebrovascular diseases

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【作者】 杨益阶唐尊立代红源高恩惠

【Author】 Yang Yijie; Tang Zunli; Dai Hongyuan,et al (Department of Neurology, The First Affiliated Hospital,Hubei Nedical University, Wuban 430060)

【机构】 湖北医科大学附一医院神经科

【摘要】 采用放射免疫法,检测了62例脑梗塞和53例脑出血急性期患者血清肿瘤坏死因子α(TNF-α)的含量。结果发现,两患者组TNF-α均明显高于对照组(P<0.001)。提示在脑梗塞和脑出血的发病过程中,都存在着TNF-α介导的免疫反应。

【Abstract】 The serum concentrations tumor necrosis factor-α(TNF -α) were measured by radioimmunoassay in 62 patients with acute cerebral infarction(CI) and 53 cerebral hemorrhage (CH ) and results were compared with those in 20 healthy controls.The levels of TNF-α in CI and CH were significantly higher than those of the controls (P<0. 001 ) . The results suggested that an immunological response mediated by TNF-α is present in the pathogenesis of both CI and CH.

  • 【文献出处】 中风与神经疾病杂志 ,JOURNAL OF APOPLEXY AND NERVOUS DISEASES , 编辑部邮箱 ,1996年05期
  • 【分类号】R743.3
  • 【被引频次】5
  • 【下载频次】23
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