【摘要】 观察了槐胺碱（SA）对正常小鼠免疫功能的影响。结果表明：SA15、20mg／kg减低胸腺重量，降低E花环形成率，抑制T淋巴细胞转化，但对脾脏重量无明显影响，也不影响脾脏溶血空斑形成。SA25mg／kg则显著降低胸腺和脾脏重量，降低E花环形成率，抑制T淋巴细胞转化。而各剂量SA均不影响腹腔巨噬细胞吞噬功能。更多还原

【Abstract】 The effects of sophoramine (SA) on immune system in normal mice were studied. SA 15. 20mg/kg reduced the weight of thymus,decreased the rate of E rosette,and also suppressed T lymphocyte transformation. The weight and the hemolytic plaque of spleen were not influenced by SA at 15. 20mg/kg. At the dose of 25mg/kg,SA reduced the weight of thymus and spleen,decreased the rate of E rosette and suppressed the T lymphocyte transformation. All of the doses of SA didn’ t affect the phagocytotic function of peritoneal macrophage.更多还原