【摘要】 ４－硝基邻苯二甲酸根桥联双核钴（Ⅱ）配合物的合成、磁性及抗癌活性石敬民，廖代正，程鹏，缪明明，姜宗慧，刘永江，王耕霖（南开大学化学系天津３０００７１）关键词硝基邻苯二甲酸根，双核钴（Ⅱ）配合物，磁性，生物活性研究桥联多核配合物的磁性不仅有助于了解桥联...更多还原

【Abstract】 Two new novel binuclear cobalt （Ⅱ） complexes, namely,[Co₂ （4PT） （Phen）₄]（ ClO₄ ）₂· 3H₂O （complex 1） and[Co₂ （4PT）（NPhen）₄] （ClO₄）₂·2H₂O （complex 2） （4PT=4-nitrophthalato , Phen=l,10-phenanthroline , NPhen = 5-nitro-1,10-phenanthroline） have been synthesized. The complexes were characterized by elemental analysis, IR, UV-Vis spectra and electronic conductance. The variable-temperature magnetic susceptibility of the complexes was measured over 77￣300 K. The data were analyzed by using the magnetic susceptibility equation based on Heisenberg spin-exchange operator, and the exchange integrals for complex 1 and complex 2 were found 2J= - 8. 6 cm￣（-1） and 2J=-4. 3 cm￣（-1）,respectively. Experiments of inhibiting human leukemia cell, stomach cancer cell and carcinoma of nasopharyngeal cancer cell in vitro were made,and found that the complexes exhibited a relatively strong function of inhibiting these three kinds of cancer cells.更多还原