【摘要】 宫糜药膜由宫糜散改制而成,两者的临床总有效率分别为96.6％和68.1％。经薄层层析对照试验,均含处方药物黄柏、青黛等相应活性成分。薄层扫描定量结果,小檗碱和靛玉红在膜剂中的含量分别为:0.798±0.024(mg/g)、0.271±0.011(mg/g);在散剂中分别为:0.791±0.023(mg/g)、0.273±0.008(mg/g),经t试验,两剂型中两活性成分含量均无显著性差异(p>0.05)。膜剂因水溶成膜材料有利药物释放,故疗效显著提高,且剂量易于掌握,使用方便。本研究为该药物的两种剂型的质控标准提供了科学依据。更多还原

【Abstract】 Filmogen for cervitis is up-graded from pulveres. Their clinical effciencies have reached96. 6% and 68. 1%. Based on TLC, they include the corresponding active constituents of cortex Phellodendriand Indigo Naturalis etc in the Prescription. The results determined by TLC-Scanner showed that content ofBerberine and Indirubin was 0.798±0. 024 (mg/g), 0. 271±0. 011 (mg/g) in Filmogen, and 0.791±0. 023(mg/g), 0.273±0. 008 (mg/g) in Pulveres. Their content in the two dosage form has no apparent differenceby "t" experiment (p>0. 05). Filmogen is beneficial to release active constituents because of its water-solu-ble phragmoid material, so its curative effect is more marked. And its dosage is controlled easily. We can useit more conveniently. This research provides the scientific bosis for the quality control of the two dosageform.更多还原