【摘要】 为比较环丙沙星与诺氟沙星治疗急性细性痢疾的疗效,将105例患者分为两组进行临床对照试验.试验组55例,给予环丙沙星口服(儿童30mg/(kg·d),tid,成人0.5g,bid或tid);对照组50例,给予诺氟沙星口服(儿童15～20mg/(kg·d),tid;成人0.2g,tid).两组治愈率和好转率分别为87.3%、12.7%和46.0%、54.0%(均P<0.01);治疗3d后细菌培养阴转率分别为87.3%和63.0%(P<0.01);治愈者疗程分别为4.27d和5.74d(P<0.01).试验结果显示环丙沙星对急性细菌性痢疾的疗效优于诺氟沙星.更多还原

【Abstract】 To compare the effects of ciprofolxacin and norfolxacin on acute bacterial dysentery, 105 patients were divided into two groups. The patients in experimental group received ciprofloxacin orally (30 mg/kg ?d, for children and 0.5g, bid or tid for adults). The patients in control group were given norfloxacin orally (15-20 mg/kg昫 for children and 0.2g, tid for adults). The cure rates and recovery rates were 87.3% and 12.7% in experimental group and 46.0% and 54. % in control group (P<0.01). The the results of bacterial culturing turned to negative in 87.3% in experimental group and 63.0% in control group (P<0. 01). Our results showed that effect of ciprofloxacin on acute bacterial dysentery was better than that of norfloxacin.更多还原