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箬叶多糖对小鼠实验性四氯化碳致肝损伤的作用

Effects of Indocalamus tessellatus polysaccharides on carbon tetrachloride induced liver injury in mice

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【作者】 陈春英丁玉强Elhag AELMAHADI周井炎李焰徐辉碧

【Author】 CHEN Chun Ying, DING Yu Qiang, Elhag A ELMAHADI 1, ZHOU Jing Yan, LI Yan, XU Hui Bi (Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074; 1Abu Haraz College, Elgazira University, Wadeni PO Box 42, Sud

【机构】 华中理工大学化学系

【摘要】 箬叶多糖对小鼠实验性四氯化碳致肝损伤的作用陈春英丁玉强ElhagAELMAHADI1周井炎李焰徐辉碧(华中理工大学化学系,武汉430074;1ElgaziraUniversity,WadeniPOBox42,Sudan)箬叶是禾本科植物箬竹(Indo...

【Abstract】 Indocalamus tessellatus polysac charides (ITPS) were extracted from the dry bamboo leaves of Indocalamus tessellatus with 85% ethanol (FE), 95 ℃ water (FⅠ), 5% NaOH (FⅢ 1, FⅢ 2) and 20% NaOH (FⅣ). Effects of these ITPS on liver of 6% CCl 4 oil solution 10 mL·kg -1 treated mice were studied. Various fractions of ITPS 80 mg·kg -1 ip respectively, once a day for 7 d significantly inhibited the MDA formation in hepatic mitochodrion and microsome, decreased the microviscosity of hepatic mitochodrial membrane and increased the SOD activity of liver. These results suggest that ITPS are protective against CCl 4 induced liver damage.

  • 【文献出处】 中国药理学与毒理学杂志 ,CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY , 编辑部邮箱 ,1996年03期
  • 【分类号】R282.710.5
  • 【被引频次】24
  • 【下载频次】82
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