【摘要】 对30例视网膜脱离（RD）患者及100名健康人进行了HLAⅠ类抗原检测，并结合临床表现进行分析，发现视网膜脱离患者全身HLA同健康人相比有变化。患者HLA－A1、A31、B5、Bw46四种抗原较正常对照组高（P＜0．05）。在RD患者中上述4种抗原阳性者PVR形成和手术失败率明显高于4种抗原阴性者（P＜0．05）。而且4种抗原中有2种以上抗原阳性者PVR的发生率增高至90％，手术失败率及视网膜脱离复发率也增至60％。结果提示视网膜脱离患者的PVR形成同全身HLA变化有一定关系。更多还原

【Abstract】 HLA-Ⅰ antigens were studied in 30 cases of patients with retinal detachment and 100 cases of normal people as a control. The results show that HLA-Ⅰ types of patients with retinal detachments are different fromthose of normal people. 4 types of antigens (HLA-A1, A31, B5, Bw45) among the patients were higher thanthat of control (P<0.05). The patients with positive antigen has more severe PVR formations and higherfailure rate of surgeries than the patients with the negative reactions (P<0. 05). The PVR formation rate among the patients with 2 of the 4 types of the positive antigen reactions is 90% and the rates of surgery failure and recurrence reached to 60% in this group. The conclusion gives the clue that PVR formation associatedwith retinal detachments may be related to general HLA changes.更多还原