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单克隆抗体检测血吸虫病人血清特异性循环免疫复合物的初步探讨

PRELIMINARY STUDIES ON THE DETECTION OF SPECIFIC CIRCULATING IMMUNE COMPLEX IN THE SERA FROM THE PATIENTS WITH SCHISTOSOMIASIS BY MONOCLONAL ANTIBODIES

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【作者】 郑志国; 楼涤; 蒋建敏; 汤益; 郁俊豪; 屠乐鸣;

【Author】 Zheng Zhiguo,Lou Di,Jiang Jianmin,Tang Yi籝u Junhao.Tu Leming Institute of Parasitic Diseases,ZheJiang Academy of medical Seiences (Hangzhou 310013)

【机构】 浙江省医学科学院寄生虫病研究所!杭州310013;

【摘要】 本文系探讨用ⅢD10McAb识别18例慢性血吸虫病患者血清CIC,并与经聚乙二醇(PEG)沉淀的CIC对照,二者结果相似.该McAb-ELISA方法检测血吸虫病慢性患者67例,46例呈阳性反应,21例呈阴性反应而对肺吸虫病患者59例、健康人23例全部呈阴性反应.初步结果表明,该方法检测血清CIC具有较高的特异性.

【Abstract】 The CIC in 18 sera of the patients with schistosomiasis was detected by McAb III D10, and the results were similar to that by PEG precipitation test. Sixty seven sera from the patients with chronic schistosomiasis were detected by McAb-ELISA,46 sera of them were positive and 21 were negative. But 59 sera of patients of Paragonimiasis and 23 sera of healthy persons were all negative by McAb-ELISA. It indicated that detection of CIC by McAb was more specifie.

  • 【文献出处】 中国血吸虫病防治杂志 ,Chinese Journal of Schistosomiasis Contral , 编辑部邮箱 ,1996年03期
  • 【分类号】R532.21
  • 【下载频次】10
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