【摘要】 本文报道对中晚期了宫颈癌17例采用动脉化疗VNAP方案同时应用放射治疗的方法和结果。化疗方案为：长春地辛4mg第1天及第8天,阿霉素40mg／m2第1天;消瘤芥20mg／日第2天至第6天；顺铂20mg／日第2天至第6天。放疗采用60Co后装腔内放疗A点50Gy；60Co外照射B点50Gy.治疗结果CR13例；PR4例。化疗反应有血液系统2例4度反应;消化系统3例呕吐反应3度，有5例发生3度腹泻。随访至1995年12月，15例存活中，2例死亡。同时，全文对动脉化疗之插管途径及药物之组合进行了讨论。本方案近期效果尚称满意，但收集病例尚少，随访时间也短，还需做进一步的探索。更多还原

【Abstract】 Seventeen cases of advanced cervical cancer were treated with concurrent intra arterial VNAP chemotherapy and irradiation. The chemotherapy regimen was as follows: Vindesine 4mg, day 1 and day 8; doxorubicin 40mg/m2, day 1; Nitrocaphane, 20mg, day 2 to day 6 and Cisplatln 20mg, day 2 to day 6. Irradiation included intracavitary after loading radiotherapy with 60cobalt for a doze of 50Gy at point A and 50Gy to point B by external irradiation with 60cobalt. After treatment, 13 cases had complete responses, while partial responses were achieved in the other 4 cases. During the course, 2 cases were puzzled by grade 4 hemopoietic reaction, 3 cases were troubled with grade 3 vomiting and the other 5 grade 3 diarrhea. Up to December 1995, 15 cases were alive and there were 2 deaths. Discussion has been focused on the routes of arterial catheterization and modes of combination of varieties of chemotherapeutic agents. The inunediate result of this series has been satisfactory, while long term follow up remains an important role for proper evaluation of this modality of treatment.更多还原