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乳腺非何杰金淋巴瘤8例临床病理及免疫表型分析

Non-Hodgkin’s lymphoma of the breast: A clinicopathologic and immunophenotype analysis of 8 patients

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【作者】 任国平许亮文余心如方淑娟丁伟

【Author】 Ren Guoping; Xu Liangwen; Yu Xinru, et al.(The First Affiliated Hospital, Zhejiang Medical University, Hangzhou 310003)(Hangzhou Medical College Hangzhou 310003)

【机构】 浙江医科大学附属第一医院!杭州310003杭州医学高等专科学校!杭州

【摘要】 本文对6例原发及2例继发乳腺NHL进行报道分析。临床易误诊为乳腺癌.在部分病例镜下可见到淋巴上皮病损。本组组织学类型大多为高度恶性。免疫级化示:原发组6例中4例为B细胞性,1例为T细胞性.1例来定;继发2例均为B细胞性。本研究示:原发与继发乳腺NHL主要靠临床区别,组织学形态难以鉴别;至少部分乳腺NHL与粘膜相关淋巴组织有关;年轻妇女乳腺NHL预后差。

【Abstract】 Non-Hodgkin’s lymphoma of breast .either primary or secondary tumor. is a rare disease. Clinicopathologic and immuno-histochemical analysis of 8 patients with breast lymphoma (6 primary. 2 secondary)was performed. These breast tymphomas could not bepredicted preoperatively. Histologically,a high incidence of intermediate and high-grade lymphmas in breast were present. Lyrnphoepithe-lial lesions were identified in some cases. Immunohistochemitully, it is observed B-cell phenotype in 5 cases, T -cell phenotype in l case andunclear type in l case. Although this study failed to demonstrate a morphologic difference between primary and secondary lrwphoma ofbreast, a relationship between primary breast lymphoma and lymponias of rnucosa-asaxiated lyrnphoid tissue has been revealed. andyoung women showed worse prognoses.

  • 【文献出处】 浙江肿瘤 ,Zhejiang Cancer Journal , 编辑部邮箱 ,1996年02期
  • 【分类号】R737.9
  • 【被引频次】1
  • 【下载频次】23
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