【摘要】 本文主要观察水蛭及丹参这两种具有抗凝抗栓作用的药物对高脂血症及内皮损伤引起的动脉粥样硬化形成的影响和此时纤溶系统某些指标的变化。结果表明：这两种药物无可抑制高胆固醇膳食家兔血清胆固醇的上升（Ｐ＜０．０５）；减轻髂动脉因粥样硬化所造成的管腔狭窄（Ｐ＜０．０５）；抑制血浆纤溶酶原浓度和纤维蛋白原浓度的升高（Ｐ＜０．０ｌ）。提示水蛭和丹参可延缓动脉粥样硬化的形成，并在一定程度上阻止此时纤溶活性的降低。更多还原

【Abstract】 This study observed the influence of Hirudo(Hirudo nipponica Whitman)and Red Sage Root(Salvia miltiorrhiza Bunge)on the atherogenesis due to hyperlipidemia and injury of artery endothelial cell and fibrinolytic activities in rabbit.It was found that these two substances not only could inhibit the increasing of serum total cholesterol(p<0.05),abatement the atheromatous lumen stenosis of iliac artery(p<0.05),but also could inhibit the increasing of plasminogen and fibrinogen in plasm of hypercholesterol diet fed rabbits.更多还原