【摘要】 对４１６例病毒性肝炎患者进行了抗－ＨＣＶ及其它血清标志物检测，结果共发现５２例抗－ＨＣＶ阳性患者，其中单独抗－ＨＣＶ阳性占２３．０％，与ＨＢＶ感染占４０．４％，与ＨＢＶ、ＨＤＶ感染占９．６％。抗－ＨＣＶ在慢性活动型肝炎、肝硬化中的阳性率分别为３０．４％和２２．７％，明显高于急性肝炎和非甲非乙型肝炎中的阳性率（２．８％、１３．０％），提示ＨＣＶ在促使肝病慢性化及加重病情方面有重要作用。对抗－ＨＣＶ阳性患者外周血Ｔ淋巴细胞分型结果显示：各型丙肝息者ＣＤ＿３、ＣＤ＿４比例均下降，而ＣＤ＿８比例上升，表现为Ｔｈ细胞功能下降，Ｔｓ细胞功能增强，提示细胞免疫功能紊乱是丙肝患者高慢性化率的免疫学基础。更多还原

【Abstract】 cases of viral hepatitis were testedfor anti- HCV and other serum marker.The anti-HCV positive patients were 52 cases,and the positiverate of anti-HCV was 23.0%。The positive rate ofanti-HCV in HBV infected patients and in HBV-HDVinfected patients were 40.4%and 9.6%respectively,The pasitive rate of anti-HCV in patients with chron-ic active hepatitis and patients with cirrhosis were30.4%and 22.7%respeetively,The rates weresingnificantly higher than that in acute hepatitis andNANB hepatitls(2.8%、13.0%).The result showedthat HCV was important in the severity of chronichepatitis。The results of T-cell typing in peripberalblood anti-HCV positive patients showed th at therate of CD4、CD3 were decreased and CD8 was in-creased in various types of hepatitis C patients,andthe Th cell fuction decreased but the Ts cel l fuctionincreased.It is considered th at th e disorder of cellu-lar immune function could increase the Chronic rate ofhepatitis。更多还原