节点文献

荧光分光光度法测定氧氟沙星片剂的含量

etermination of ofloxacin in tabletsby fluorospoectrophotometry

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 刘新泳张君仁王德凤任健田心

【Author】 Liu xinyong, Zhang Junren,Wang Defeng, Ren Jian and Tian Xin(Department of Pharmaceutical Analysis, Shandong Medical University, Ji’ nan 250012)

【机构】 山东医科大学药物分析教研室

【摘要】 用荧光分光光度法测定氧氟沙星片剂的含量。选用0.05mol/L盐酸为溶剂,在Ex=293nm、Em=507nm处测定荧光强度。在0.10~0.35ug/ml范围内,荧光强度与浓度呈线性关系,回归方程为C=0.0736F—0.0069(r=0.9998)。平均回收率为99.53%,RSD为0.89%(n=8)。本法灵敏度高,操作简便,结果准确。

【Abstract】 This article reported the assay of ofloxacin tablets by fluorospectrophotometry. Hy-drochloride acid solution was selected as solvent and Ex293nm and Em507nm were set. There was agood correlation between fluoresent value and concentration ranging from 0. 10μg/ml to 0. 35μg/ml.The regression equation was C= 0. 0736F- 0. 0069 (r= 0. 9998). The average recovery was 99.53 %, RSD= 0. 89 % (n= 8). This method is sample, sensitive and accurate.

【关键词】 氧氟沙星荧光分光光度法
【Key words】 ofloxacinfluorospectrophotometry
  • 【文献出处】 西北药学杂志 ,NORTHWEST PHARMACEUTCAL JOURNAL , 编辑部邮箱 ,1996年03期
  • 【分类号】R927.2
  • 【被引频次】3
  • 【下载频次】159
节点文献中: 

本文链接的文献网络图示:

本文的引文网络