【摘要】 用离子选择电极电位法研究了镉和铜与人白蛋白（ＨＳＡ）的配合平衡。证实镉与ＨＳＡ形成了单核配合物Ｃｄ·ＨＳＡ和Ｃｄ·ＨＳＡ２，其稳定性积β１１＝５．７×１０４，β１２＝１０５×１０１０；铜与ＨＳＡ仅形成ＣＵ·ＨＳＡ，其稳定常数Ｋ＝１．６×１０９，校正了平衡渗析法的测定值（Ｋ＝１．５×１０１６）更多还原

【Abstract】 The complex equilibria for cadmium and copper with human albumin(HSA)are studiedwith ion-selective electrodes.It is clearly proved that mononuclear complexes Cd.HSA and Cd. HSA2are formed by Cd2+ with HSA,the stability products of which are β11=5.7×105andβ12=1.5×1010while only Cu.HSA is formed by Cu2+with HSA whith a stability constant K of l’6X109,which ismuch smaller than the K=1.5×1016 determined by S.J.Lau using equilibium dialysis.更多还原