【摘要】 应用花生凝集素对150例指检获取的直肠粘液进行T抗原检测,在70例大肠癌中阳性者36例(51.4％),在30例大肠息肉中阳性者8例(26.7％),而50例大肠粘膜正常者仅3例阳性(6％)。本组资料表明,该法对大肠癌检出的敏感性为51.4％,特异性为94％,阳性预测值为76.6％,而且该试验简便快速,可望用于大肠癌的筛检。更多还原

【Abstract】 Peanut agglutinin (PNA) was employed to detect T-antigen presented in rectal mucus of 150 cases obtained by digital rectal examination. Positive response was observed in 36 of 70 patients (51.4%) with colorectal cancer and 8 of 30 patients (26.7%) with colorectal polyp, only 3 showed positive response (6%) in 50 normal subjects. The results suggested the sensitivity to cancer was 51.4%, specificity, 94% and predictive value of positive test, 76.6%. The test will be useful for mass screening of colorectal cancer because it is simple, rapid and technically convenient.更多还原