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小儿肾病综合征血浆脂蛋白及载脂蛋白变化

Changes of Plasma Lipoprotein and Apolipoprotein in Children with Nephrotic Syndrome

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【作者】 杨凤英王忠玲宋其桂翟淑萍

【Author】 Yang Fengying.Wang Zhongling,Song Qigui, Second Hospital,Tianjin Medical University

【机构】 天津医科大学第二医院天津医科大学第二医院 300211300211300211

【摘要】 测定46例小儿肾病综合征血脂6项,以24例健康儿作对照。结果发现:极期LDL-C(3.83倍),T-Ch(2.95倍)、Apo-B100(2.53倍)及TG均升高;而HDL-C及Apo-A变化则不显著(P>0.05)。缓解期上述4项血脂水平有所下降,但仍高于对照组,而HDL-C水平上升,有统计学意义。笔者认为,治疗本病应根据极期持续时间及血脂变化,适时适量采用降脂疗法。

【Abstract】 Six kinds of plasma lipids were determined in 46 cases with nephrotic syndrome (NS) and 24 healthy children as controls. The results revealed that the values of LDL-C,T-ch, Apo-Bioo and TG in fastigium patients were signific antly higher than those of the control group (P<0. 01),about 3. 83,2. 95,2- 53 and 2. 47 times respectively,while HDL-C and Apo-A had no manifest differences (P>0. 05). In remission phrase,the levels of first 4 kinds were somewhat reduced,but still higher than normal levels,but HDL-C increased (P< 0. 05).The hypolipidemic therapy should be applied in NS children to correct plasma lipid abnormalities.

  • 【文献出处】 天津医药 ,Tianjing Medical Journal , 编辑部邮箱 ,1996年03期
  • 【分类号】R726.91
  • 【被引频次】2
  • 【下载频次】9
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