【摘要】 采用免疫组化技术，辅以形态观察，研究３０例肝硬变患者胃冠状静脉的病理变化。发现其内膜受损，组织炎性水肿，中膜平滑肌增殖肥大，细胞外基质增多，管壁因而纤维化、硬化并增厚。表明肝硬变门静脉高压症可合并“门脉高压性血管病变。”更多还原

【Abstract】 The purpose of present study is to assess the pathological changes of gastric coronary vein in cirrhotic patients (n=30) and non-cirrhotic patients (n=10) with immunohistochemistry and Masson trichrome stain. The authors found that there were damage to endothelium, hypertrophy and hyperplasia of vascular smooth muscle cell (VSMC) and increment of extracellular matrix (ECM)in gastric coronary vein of cirrhotic patients, Compared with non-cirrhotic patients, the blood vessel walls became hardened and thickened with decrement of elasticity in cirrhotic patients. The results show that the portal hypertention could be accompanied with pathological changes of portal vein system which we define as "portal hypertensive vasculopathy".更多还原