【摘要】 应用全细胞膜片钳技术，证明大鼠背根神经节（ＤＲＧ）中有７０．３％的细胞对Ｎ－甲基－Ｄ－天冬氨酸（ＮＭＤＡ）敏感，１８．９％的细胞对红藻氨酸（ＫＡ）敏感，５６．８％的细胞对使君子酸（ＱＡ）敏感，并观察到Ｍｇ（２＋）及甘氨酸（Ｇｌｙ）仅对ＮＭＤＡ激活电流有影响，而对ＫＡ和ＱＡ激活电流无作用。更多还原

【Abstract】 The whole-cell patch-clamp technique was used to record excitatory amino acid-activated currents in freshly isolated dorsal root ganglion neurons.It has been shown in the present study that there were different populations of neurons sensitive to N-Methy1-D-Aspartate (NMDA)(70.3%),Kainate(KA)(18.9%)and Quisqualate(QA)(56.8%)in dorsal root ganglion respectively,and different effects of Mg2+ and glycine on subtypes of glutamate receptor were observed.更多还原