【摘要】 用沙土鼠30只,随机分为两组,夹闭双侧颈总动脉致前脑缺血后再灌流性脑损伤。两组均于右侧大脑皮质体感区注入25％HRP 20μl。实验组动物腹腔注射双胸蚓溶栓酶(bimastos thrombolytic enzyme,BTE)10ml,而对照组动物腹腔注射生理盐水10ml。心脏灌流固定,取材,冰冻切片,行TMB法呈色反应,光镜下观察。结果表明:实验组15例150张切片中丘脑标记细胞总数为2221个,平均为14.8个;对照组15例15O张切片中丘脑标记细胞总数为838个,平均为5.59个,两组差异非常显著(P<0.01)。更多还原

【Abstract】 30 Mongolian gerbils were divided into two groups by random sampling and models of cerebral reperfusiohi inijucy, in anterior’cerebrums were produced. Then BTE 1.0ml and normal saline 10ml was injected into the cavitas abdominis in the test group and control group respectively. HRP 20>d was injected into the idmesthetic area. -The sections of the thalatnus through TMJJ dyeing were studied under the light micrbsdope. The results showed that the sum tatal of the marked cefls in 150 fiims in the test group was 2221 粫 with an average of’14. 8, and it was 838 and S. 95 in the control group. The difference between them was statistically significant CP<0. 01).更多还原