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脑动脉粥样硬化和脑血栓者血浆D-二聚体检测及临床意义

The Clinical significance of measurement of plasma D dimer in patients with cerebral atherosclerosis and atherothrombotic stroke

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【作者】 郭宗君石秉霞金丽英

【Author】 Guo Zongjun,Shi Bingxia,Jin Liying.The Cerebrovascular Institute of Qing Dao Medical College,Qingdao 266003

【机构】 青岛医学院脑血管病研究所

【摘要】 检测32例脑动脉粥样硬化和28例脑血栓病人血浆D-二聚体含量,并与33例年龄匹配的健康人(对照组)比较。结果D-二聚体含量在对照组为0.43±0.26mg/L;脑动脉粥样硬化组与脑血栓形成组(病后<7d、4w、6w3个时期)血浆D-二聚体含量分别为0.86±0.48、1.02±0.97、1.07±1.04和1.05±0.87mg/L,与对照组相比均明显升高(P均<0.001),但脑动脉粥样硬化和脑血栓形成两组之间无显著差异(P>0.05)。认为D-二聚体可作为检测血栓前状态和病情判断的指标。

【Abstract】 The plasma concentrations of D dimer were measured in 32 cases of cerebral atherosclerosis and 28 cases of atherothrombotic stroke,and were compared with those of 33 controls.A marked elevation of plasma concentrations of D dimer were observed in cerebral atherosclerosis and in atherothrobosis at all periods ( P <0 001) as compared with the controls.No significant difference was found between the data of these 2 groups.D dimer may be used as a marker to detect the prothrombosis state and to judge the condition of the illness.

  • 【文献出处】 实用老年医学 ,PRACTICAL GERIATRICS , 编辑部邮箱 ,1996年06期
  • 【分类号】R743.1
  • 【被引频次】10
  • 【下载频次】48
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