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核素肾动态显像评价巯甲丙脯酸治疗对原发性高血压患者肾功能的影响

Assessment of the effect or captopril on renal function in patients with essential hyperten-sion by the use of radionuclide renal dynamic imaging

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【作者】 杨红; 晋建华; 王进; 张承刚;

【Author】 Yang HOng; Jin Jianhua; Wang Jin et al(Dept.of Nuclear Medicine, 1st Affiliated Hospital, Shanxi Medical College,Taiyitan,030001)

【机构】 山西医学院第一附属医院核医学科;

【摘要】 用核素肾动态显像对17例原发性高血压患者单用巯甲丙脯酸治疗4.7月前后的肾功能进行了动态观察。结果表明:巯甲丙脯酸治疗后绝大多数病例的血压降至正常,肾显像指标全肾平均通过时间及高峰时间明显缩短(P<0.01),血肌酐降低(P<0.05),血尿素氮变化不大。说明巯甲丙脯酸在满意降压的同时可使原发性高血压患者的肾功能改善;核素肾动态显像是-较灵敏的反映肾功能动态变化的检测方法。

【Abstract】 he effect of captopril on renal function was assessed in 17 patients with essential hyper-tension,by using radionuclide renal dynamic imaging. The results showed that the bloodpressure of almost all the patients with EH became normal, kidney mean transit time andtime to peak were significantly shortened(P<0.01), creatinine was dropped (P<0.05)and the blood urea nitrogen had little change. It suggested that captopril could improve therenal function of the patients with EH as it decreased the blood presstire. The radionucliderenal dynamic imaging was a sensitive method for assessment of the dynamic change of therenal function.

  • 【分类号】R544.02
  • 【被引频次】1
  • 【下载频次】23
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