节点文献
PC-12细胞离子单通道开放状态的检测
THE DETECTION OF OPEN STATE OF K~+ CHANNEL OF PC-12 CELL
【摘要】 本文对用片膜钳技术记录的PC-12细胞钾通道数据进行了连续分组平均开放时间分析,检测到通道活动的三种开放状态.并用正态密度函数对通道平均开放时间的频数分布进行了拟合,估计了各状态的开放持续时间的均值、方差等参数.本文提供的方法,在通道的数据分析中具有广泛的应用价值.
【Abstract】 Using the method of mean open durations of consecutive groups,the patch clamp recording of K~+ channel of PC-12 cell was analysed,Three open states of the channel activities were detected,the frequency distribution of mean open durations was fitted with normal densities of probability,and the mean and variance of each states were estimated.The method introduced in the paper is very useful for the patch clamp recording of ion channel.
【基金】 国家自然科学基金
- 【文献出处】 生物数学学报 ,Journal of Biomathematics , 编辑部邮箱 ,1996年02期
- 【分类号】Q2-3
- 【被引频次】5
- 【下载频次】50