【摘要】 目的：研究石蜡包埋癌组织制备的自体瘤苗（ＰＥＴＶ）预防膀胱癌术后复发的近期效果。方法：ＰＥＴＶ１．０ｍｌ多点皮内注射，每周１次，４次为一疗程。每疗程前后测定ＣＤ３＋、ＣＤ４＋、ＣＤ８＋、ＣＤ４＋／ＣＤ８＋、ＬＴＴ、ＮＫ和ＩｇＡ、ＩｇＧ、ＩｇＭ。结果：１６例患者治疗后ＣＤ３＋、ＣＤ４＋、ＣＤ４＋／ＣＤ８＋、ＬＴＴ、ＮＫ和ＩｇＧ比治疗前明显增高（Ｐ＜０．０５）。随访１２～２０个月，未见肿瘤复发。结论：ＰＥＴＶ抗原容易获得，用以预防膀胱癌术后复发近期效果满意更多还原

【Abstract】 OBJECTIVE:To study the shortterm recurrencepreventive effect of autologous tumor vaccine prepared from paraffinembedded cancer tissue (PETV) on bladder neoplasm operated.METHOD:PETV was administered intracutaneously once a week at a dose of 1.0mg,4times constituting a single treatment course.CD 3 +,CD 4 +,CD 8 +,CD 4 +/CD 8 +,LTT,NK,IgA,IgGand IgM were measured before and after the treatment course,respectively.RESULTS:After treatment,the parameters of CD 3 +,CD 4 +,CD 4 +/CD 8 +,LTT,NK and IgG of 16 patients increased significantly ( P <0.05) .No recurrencewas found during a followup for a period of 12～20 months.CONCLUSION:The antigen of PETV is preserved easily.It has a satisfactory shortterm effect in preventing recurrence of bladder neoplasm.更多还原