【摘要】 对肺心病急性发作期患者联合使用蛇毒抗栓酶Ⅲ号和常规疗法进行治疗，并与单纯常规疗法作对照。结果表明蛇毒组的部分缓解所需天数明显少于对照组（Ｐ＜０．０１），组织型纤溶酶原激活物（ｔＰＡ）和６－酮－前列环素（６－Ｋ－ＰＧＦ１α）含量明显高于对照组（Ｐ＜０．０１，Ｐ＜０．０１）。提示蛇毒抗栓酶可能通过提高ｔＰＡ及６－Ｋ－ＰＧＦ１α含量纠正高凝状态和纤溶功能低下，使基础治疗更能发挥作用。更多还原

【Abstract】 In this article,the patients with pulmonary heart disease at acute attack phase were treated with snake venom antithrombotic enzyme-3(Svate-3)combining routine treatment,contrasting with patients treated with routine therapy along.The results showed after treatment with Svate-3 combining routine therapy group, The days for partial remission were obviously less than in control group(P<0.01).The contents of tissue-plasminogen activator(tPA) and 6-k-PGF1α were obviously higher than in control group (P<0.01;P<0.01).The activity of plasminogen activator inhsbitor(PAI) was reduced tendenly (P>0.05).It was showed that Svate-3 could correct hypercoagulability and improve fibrinolysis function by raising the contents of tPA and 6-k-PGF1α, so it could improve the basal treatment.更多还原