【摘要】 本文研究用大网格吸附剂从发酵液中提取抗生素Ｍ－９０的吸附与解吸过程。包括：吸附剂、解吸剂的选择，加盐对吸附情况的影响，以及吸附条件和解吸条件的筛选等。结果表明，ＣＡＤ－４５为最佳吸附剂，吸附最佳ｐＨ为８．０；流速选择０．５ｍｌ／分；加３％ＮａＣｌ对吸附有利，最佳解吸剂为ｐＨ６．０９５％乙醇。在本实验条件下，当吸附液中Ｍ－９０浓度为２３０Ｕ／ｍｌ左右时，ＣＡＤ－４５对Ｍ－９０的吸附量达２．２２万Ｕ／ｍｌ吸附剂，吸附率为９６．８２％，解吸率为９３．７８％，收率为９０．８０％。更多还原

【Abstract】 The adsorption and desorption extraction processes of macrolide antibiotic M- 90 from the fermentation broth by macroreticular adsorbents are discussed. The experimental conditions such as adsorbents, eluants and other relevant factors are selected and determined in the experiments.The results appeared that the adsorbent CAD- 45 had the highest static adsorption capacity of antibiotic M- 90 ;the pH is maintained at 8. 0 ; flow rate of adsorption is 0.5ml/min; 3 % NaCl is added to the fermentation broth ;and the optimum eluant is 95% EtOH.The experiments also show that the dynamic adsorption capacity of antibiotic M - 90 onto the CAD- 45 adsorbent is 2. 22 × 104U/ml of resin ; with 96. 82% for the adsorption rate, 93. 78% for the elution rate and 90. 80% for the efficiency.更多还原