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环孢霉素A合并雄激素治疗成人重型再生障碍性贫血

Cyclosporin A in Combination with Androgens Treatment for Patients with Severe Aplastic Anemia

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【作者】 陈琳军林果为林佩娣

【Author】 Chen Linjun,Lin Guowei,Lin PeidiAffiliated Huashan Hospital,Shanghai Medical University

【机构】 上海医科大学华山医院上海医科大学华山医院 200040200040

【摘要】 采用环孢霉素A(CsA)合并雄激素(康力龙、安雄或丙睾)治疗13例重型再障(SAA)和1例重型纯红再障(PRCA),总的近期有效率64.3%,SAA有效率61.5%,1例PRCA达基本治愈。多数病例能保持近期疗效。SAA-Ⅰ型有效率(83.3%)明显高于SAA-Ⅱ型(42.9%)。认为CsA合并雄激素治疗重型再障是适合国情,有效、安全、方便的治疗方案。

【Abstract】 Thirteen patients with severe aplastic anemia (SAA) and one patient with severe pure red-cell anemia(PRCA) received therapy consisting of cyclosporin A (CsA) and androgens (stanozololi,andriol,testosterone propionate). The whole recently effective rate (ER) was 64. 3%. The ER of SAA was 61. 5%,one PRCA was in fundamental remission. Most patients could maintain their recently ER. The ER of SAA- I (83. 3%) was extraordinarily higher than that of SAA-II(42.9%). It was suggested that CsA in combination with androgens in SAA is a suitable,effective,safe and easy treatment in our country.

【关键词】 贫血再生障碍性环孢霉素A
【Key words】 Anemiaaplastic Cyclosporin A
  • 【文献出处】 临床血液学杂志 ,Journal of Clinical Hematology , 编辑部邮箱 ,1996年03期
  • 【分类号】R556.5
  • 【被引频次】17
  • 【下载频次】45
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