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急性脑血管病患者下丘脑-垂体-肾上腺皮质轴与性腺轴功能研究

Functional Study of Subthalamic-Pituitary-Adreno-Cortical Axis and Subthalamic Pituitary-Gonado Axis in Patients with Acute Cerebrovascular Disease

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【作者】 李义召郭洪志迟兆福苑仁毅

【Author】 LI Yi-Zhao, Guo Hong-Zhi, Chi Zhao-FuDepartment of Neurology, the Affiliated Hospital of Shandong Medical University, Jinan, 250012

【机构】 山东医科大学附属医院山东医科大学附属医院 250012250012250012

【摘要】 急性脑血管病(ACVD)患者的PRL、GH、ACTH、LH、FSH及F水平均显著高于对照组;ACVD并发多器官功能衰竭(MOF)患者,除LH外,余5种激素水平显著高于ACVD各疾病组;随ACVD病程不同,9种激素水平也相应改变,1周时水平最高,2周后逐渐恢复;ACVD并发MOF重型患者(MOF积分>4分)PRL、GH、F水平显著高于轻型患者(MOF积分≤4分)。结果提示PRL、GH和F可能参与ACVD并发MOF的病理生理过程。

【Abstract】 In 167 patients with acute cerebrovascular diseases (ACVD) by radioimmunoassay the levels of PRL, GH, ACTH, LH, FSH and F were significantly higher than those of the controls, the levels of PRL, GH, ACTH, FSH and F in patient with ACVD companied by MOF were higher than in the patients with acute cerebrovascular diseases, the abnormal parameters tended to recover to a great extent after improvement of clinical symptoms. The levels of PRL, GH and F were higher in severe than in mild patients with ACVD companied by MOF. These results suggested that PRL, GH and F might be involved in the pathophysiological process of ACVD companied by MOF.

  • 【文献出处】 临床神经科学 ,Chinese Journal of Clinical Neurosciences , 编辑部邮箱 ,1996年02期
  • 【分类号】R743.3
  • 【被引频次】7
  • 【下载频次】50
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