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氯胺酮、安氟醚麻醉对子宫切除术患者血浆心钠素、肾素、血管紧张素和醛固酮的影响

Effect of Ketarmine-Enflurane Anesthesia on the Levels of Plasma Atrial Natriuretic Peptide, Renin Activity, Angiotensin and Aldosterone in Patients Undergoing Hysterectomy

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【作者】 马占文王天元姜亚昌

【Author】 Ma Zhan-wen, et alDepartment of Anesthesiology, Third Teaching Hospital, Norman Bethune University of Medical Sciences

【机构】 白求恩医科大学第三临床学院麻醉科四平市卫生学校附属医院 长春市邮政编码:130021长春市邮政编码:130021

【摘要】 本文研究了氯胺酮、安氟醚麻醉对子宫肌瘤切除术患者血浆心钠素(ANP)、肾素(PRA)、血管紧张素(AⅡ)和醛固酮(AL)水平的影响。通过15例子宫肌瘤切除术患者的临床观察,结果表明,子宫肌瘤手术患者氯胺酮、安氟醚麻醉后10min、30min、1h和术毕ANP显著高于麻醉前(P<0.05);PRA与麻醉前比较有升高趋势;AⅡ在麻醉后30min至术毕显著低于麻醉前(P<0.05);血浆AL自麻醉后10min开始升高,至麻醉后1h和术毕非常显著升高(P<0.01)。本文还讨论了它们之间的相互关系。

【Abstract】 The effect of the ketamine,enflurane anesthesia on the levels of plasma atrial natriuretic peptide(ANP) , renin activity (PRA). angiotensin I (A I ) and aldosterone(AL) was studied in 15 patients of hysterectomy. Results show that the levels of ANP tested at 10 min, 30 min, 60 min after ketamine-enflurane ansthesia and at the end of operation were significantly higher than that before anesthesia (P<0. 05). PRA tended to rise as compared with that before anesthesia. From 30 minutes after anesthesia to the end of operation A I were lower than that before anesthesia (P<0. 05). Plasma AL began to rise at 10 min after anesthesia, and increase significantly at 60 min after anesthesia till the end of operation, as compared with that pre-anesthesia (P<0. 01). Their correlations were discussed.

  • 【文献出处】 临床麻醉学杂志 ,The Journal of Clinical Anaesthesiology , 编辑部邮箱 ,1996年02期
  • 【分类号】R614
  • 【下载频次】37
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