【摘要】 本研究观察了各期高血压病患者红细胞膜磷脂各成分的变化。结果表明,在各期高血压组红细胞膜磷脂中神经磷脂(SM),磷脂酰胆碱(PC),磷脂酰丝氨酸(PS)和SM/PC比值均明显增高,磷脂酰乙醇胺(PE)则显著降低,并且各指标改变与病情轻重有关。提示,红细胞磷脂成分异常通过影响红细胞的性能,参与原发性高血压的发生和发展。更多还原

【Abstract】 The changes in erythrocyte phospholipidsin in the patients with hypertension at each stage were observed. The results showed that the levels of sphingomyolins (SM), phosphatidylserine (PS),and phosphatidychiolines (PC),and the SM/PC ratio of erythrocyte phospholipids were sig- nificantly increased, phosphatidylchamolanine (PE) was remarkably decreased and the change of each index was relative to the extent of illness. It is suggested that the abnormal constitution of erythrocyte phospholipids involves the development of hypertension by effect on erythrocyte properties.更多还原