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血管紧张素原基因多态位点AGT235在中国人群中的分布特点
The distribution feature of angliotensinogen gene polymorphism site AGT235 in Chinese populations
【摘要】 本文采用聚合酶链反应(PCR)。限制性酶切和电泳分型方法,首次在109例中国人群中检测了血管紧张素原多态位点AGT235的分布情况。AGT235基因频率为0.7431,表现型频率为T235/2550.5431;T235/M2350.4036,M235/M2350.0550,其表现型频率分布符合Hardy-weinberg平衡
【Abstract】 The distribution of angiotensinogen gene AGT235 polymorphism site was detected in 109 cases of Chinese population by polymerase chain reaction (PCR) restriction enzyme analysis and elec- trophoresis methods to determine the genotypes the results showed tht the gene frequence of T235 was 0.7431. The genotypes frequence T235/T235 0. 5413, T235/U235 0.4036235/M235 0.0550 and the populations was equelibrium for Hardy-weinberg law exam.
【关键词】 血管紧张素原基因;
AGT235;
多态位点;
聚合酶链反应;
【Key words】 angiotensinogen gene; AGT235 polymorphism site; PCR;
【Key words】 angiotensinogen gene; AGT235 polymorphism site; PCR;
- 【文献出处】 佳木斯医学院学报 ,Journal of Jiamusi Medical College , 编辑部邮箱 ,1996年02期
- 【分类号】R394
- 【被引频次】1
- 【下载频次】9