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41例乙型病毒性肝炎患者19项免疫指标分析

19-immunoindex Analysis of 41 Patients with Viral Hepatitis B

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【作者】 王志光明洪辛西平胡石秀曾卫玲

【Author】 Wang Zhiguang Ming Hong Xin Xiping Hu Shixiu Zeng Weilin(Department of Clinical immunology,the First Affiliated Hospital,Kunming Medical College,Kunming 650032)

【机构】 昆明医学院第一附属医院临床免疫研究室

【摘要】 用间接免疫荧光、免疫透射比浊法检测各型乙肝患者的19项免疫指标,结果CD%,CD/CD 比值与正常对照相比有显著差异(P<0.001,P<0.01,P<0.05)。AH组CD+CD一CD结果与CAH,CPH组相比均有显著差异(P<0.01,P<0.05)。B细胞无组间差异。3组患者PBL绝对数>1200/mm3;组间比较,仅AH与CPH组差异显著(P<0.05)。Ig,C3,C4与正常组比较,IgG升高(P<0.05),C4降低(P<0.0l).CAH,CPH组IgM较AH组高,C4较AH组低,CAH较CPH组更低,均具统计学意义。结果表明,CD细胞降低是引起乙肝患者肝细胞损伤首要的免疫因素。

【Abstract】 Nineteen immunoindexes of subtypes of hepatitis B were determined with the methods of indirect immunofluorescence and immunotransission turbidimetry.The percentage ofCD to CD revealed a significant difference in contrast with the normal group( P<0.001,P<0.01,P<05).The significant difference was also observed in the value of CD +CD-CD,when AH group was compared with CAH and CPH groups(P<0.0l,P<0.05)。There was no marked difference for B cell among all the groups. PBL absolute number was morethan l 200/mm3 among the patients from the three groups,with obvious difference(P<0.05 ) seen between AH and CPH groups. When lg , C3 and C4 were compared with those fromthe normal group,the level of lg increased(P<0.05)but that of C4 decreased(P<0.01). IgM level was higher in CAH and CPH groups than in AH group while C4 level was lower in theformer than in the latter,and even lower in CAH than in CPH groups. They all had a statisticalsignificance.The result suggested that the decreasing of CD cells is the primary immunocause ofhepatocellular injury for hepatitis B patients.

【关键词】 乙型病毒肝炎分型免疫指标
【Key words】 Viral hepatitis BSubtypeImmunoindex
  • 【文献出处】 昆明医学院学报 ,ACADEMIC JOURNAL OF KUNMING MEDICAL COLLEGE , 编辑部邮箱 ,1996年04期
  • 【分类号】R512.620.3
  • 【下载频次】14
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