【摘要】 本文用高灵敏的免疫放射法(IRMA)测定血清促甲状腺激素(TSH),观察了某些甲状腺疾病患者的TSH昼夜节律。正常人具有TSH昼夜节律的特征。Graves病、继发性甲减、Graves眼病和部分非毒性结节性甲状腺肿患者TSH昼夜节律消失。原发性甲减患者TSH昼夜节律同正常人相似。研究结果表明,测定TSH昼夜节律有助于某些甲状腺疾病的诊断和鉴别诊断。更多还原

【Abstract】 With the ultrasensitive immunoradiometric assay, the circadian variations of serum TSH concentration and TRH stimulating test have been observed in patients with various thyroidal diseases. The circadian rhythm of TSH exists in normal subjects. It disappears in patiens with Graves disease, secondary hypothyroidism, Graves ophthalmopathy and a part of nontoxic nodular goitre. The circadian rhythm of TSH of primary hypothyroid patients is same as normal subjects. Results show:Observation of the circadian rhythm of TSH is helpful to diagnose and distinguish some thyroid disease.更多还原