【摘要】 本研究用实验流行病学方法,按随机分配原则对比了TCu380A、TCu220三球头、MLCu375SL、含药宫铜IUD四种宫内节育器(以下简称IUD)在江苏省育龄妇女中的使用效果。从1991年10月至1992年3月随机放置四种IUD,其中:TCu380A 593例,TCu220三球头606例,MLCu375SL 600例,含药宫铜IUD601例,共计2400例,农村、城市受试对象各为1200例。置器24个月时四种IUD累积续用率分别为:TCu380A 87.34/百妇女年,TCu220三球头88.41/百妇女年,MLCu375SL 87.32/百妇女年,含药宫铜型88.18/百妇女年,组间比较无显著差异(P>0.05);因妊娠、脱落、出血/疼痛终止率,四种IUD间均无显著差异;含药宫铜IUD明显降低出血副反应的发生率;按城、乡分组在24个月时农村组续用率较高,对此结果进行了探讨。更多还原

【Abstract】 IUDs have been widely used in Jiangsu province. For the purpose of comparing the efficacy of the new IUDs, TCu380A, TCu220 with three bulb at each end of the frame(TCu220A) ,MLCu375SL and Uterine shaped copper IUD with indomethacin (UCDE) were inserted in parous women randomly from October, 1991 to March, 1992. The total number was 2400 and evenly arranged in cities and rural areas. The study has been carried out for 2 years,the results showed that: the cumulative continuation rates for the 4 IUDs were TCu380A 87. 34 per 100 women years, TCu220△ 88. 41, MLCu375SL 87. 32 and UCDE 88. 18 respectively (P>0. 05) (there were no differences of pregnancy rate, expulsion rate and removal rate of pain/bleeding between the 4 IUDs. The side effect of bleeding for UCDE -was significantly reduced. In the 2 years,the rural women had a higher cumulative continuation rate and the reasons will be explored in the future studies.更多还原