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善得定与垂体后叶素治疗食管静脉曲张破裂出血的疗效对比

Clinlcal Observations of Comparing the Effects of Sandostatin and Pituitrin on Esophageal Variceal Bleeding

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【作者】 石巍刘迪群刘江华

【Author】 Shi Wei; Liu Diqun; Liu Jianghua(The First Affiliated Hospital, Hengyang Medical College, Hengyang 42l001)

【机构】 衡阳医学院第一附属医院

【摘要】 本文用善得定(sardostatin)治疗18例肝硬化食管静脉曲张破裂出血(EVB)。同期用垂体后叶素进行对比观察。结果显示:善得定治疗EVB止血总有效率为88.9%,垂体后叶素为55.6%;善得定平均止血时间为38分,垂体后叶素为74分;善得定治疗后平均失血量为325ml,垂体后叶素为568ml,两者相比疗效具有显著性差异(P<0.05)。善得定的副作用也明显少于垂体后叶素。因此,善得定可作为治疗EVB的首选药物之一

【Abstract】 This study aimed at comparing the effects of sandostatin(n=18)and pituitrin(n=18)on esophageal variceal bleeding(EVB). The results showed: The total effective hemostatic rate of sandostatin and pituitrin was 88.9% and 55.6% respectively. The mean hemostatic time of sandostatin and pitutrin was 38 minutes、74 minutes respectively. The mean amount of hemorrhage of sandostatin and pituitrin was 325ml、568ml respectively after administration. There was significant different effect between the sandostatin and pituitrin(P<0.05 ). It is suggested that sandostatin is superior to pituitrin in treatment of EVB with less adverse effect.

【关键词】 善得定食管静脉曲张破裂出血
【Key words】 sandostatinesophagealvariceal bleeding
  • 【文献出处】 衡阳医学院学报 ,JOURNAL OF HENGYANG MEDICAL COLLEGE , 编辑部邮箱 ,1996年03期
  • 【分类号】R977.1
  • 【下载频次】11
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