【摘要】 采用ＡＢＣ免疫组化染色和图像分析技术，检测了口腔粘膜异常增生及鳞癌中表皮生长因子受体（ＥＧＦＲ）表达情况。正常口腔粘膜中，ＥＧＦＲ仅见于上皮基层和近基层。粘膜异常增生时，ＥＧＦＲ表达范围随异常增生程度加重而扩展至上皮棘层及表层。鳞癌时几乎所有细胞均有ＥＧＦＲ超量表达，但染色程度不均。图像分析进一步表明，从正常粘膜、轻、中、重度异常增生粘膜到鳞癌，细胞中ＥＧＦＲ相对含量呈现显著递增。由此提示，ＥＧＦＲ表达与口腔癌发生过程有关，可作为评估口腔上皮恶变潜能的有用标记物。更多还原

【Abstract】 The epicardium of calf is a kind of membrane in which the protein, fat and carlohydrate were put out. The membrane is easy to be sutured and its strength is good. The epicardium of calf has been used as the replaeements of values in heart surgery. There is no ideal method for the patients with ankylosis of TMJ at present. The authors used the epicardium of calf as greft that was placed between sections of mandibular bone. The membrane covered the section and limited the synostosis of bones. This article reported an observation on the clinical efficacy of treatment of 11 cases with ankylosis of TMJ, in which 10 patients were considered success, they could open the mouth 3～4 cm, one case was fail, because the area of operation was infected.更多还原