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毛皮动物用转移因子的研究与应用

Studies and a pplying on the transfer factor of fur animal

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【作者】 刘润珍李世雄姜力许树林金煜李雁冰野飞飞

【Author】 Liu Tenzhen, Li Shxiong, Jiang Li, Xu Shuling, Jing Yu, Li Yianbing, Ye Feifei (The wildlife Research institute of Hei Jiang province Harbin· 150040)

【机构】 黑龙江省野生动物研究所

【摘要】 在人医转移因子研究的基础上,进行了猪脾细胞特异性转移因子(TF-P)的研究。经测定核糖含量720μg/单位,多肽含量>300μg/单位,理化指数达到了人医转移因子的标准。经一系列生化及体内外实验证明,该制剂可以提高小白鼠腹腔巨噬细胞的吞噬功能和E玫瑰花形成率。通过药理、毒理实验,证明该药无毒副作用,临床应用对犬等毛皮动物的细小病毒肠炎和犬瘟热病治疗效果显著。由于该制剂加入赋型剂经冷冻干燥后,去掉水分,质量稳定,便于保存运输,适合在兽医临床推广应用

【Abstract】 The specific transfer factor of pig spleen cell had been studied on the basis of medical transfer factor. Ribonueleotide of itis more than 720μg unit and polypeptide is more than 300μg/unit.The physical and chemical index equal to medical transfer factor. It had been proved that it could improve the engulf function of macrophage ofsmall white rat abdominal cavity and form rate of E-Rosette by a serialbiochemical experiments and in or out body experiments. It also had been proved not to have sideeffect by the toxicology and pharmacologyexperiments. It is very effect to parvovirus enteritis and caninedistemper of dag and other fur animal. For the medicine with in a safeguard pharmaceutical have been forozen and dried, it is steady amdcovenient to apply to clinic.

【基金】 黑龙江省科委攻关课题项目
  • 【文献出处】 黑龙江畜牧兽医 ,HEILONGJINAG JOURNAL OF ANIMAL SCIENCE AND VETERINARY MEDICINE , 编辑部邮箱 ,1996年08期
  • 【分类号】S865.2
  • 【被引频次】28
  • 【下载频次】103
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